Wednesday, 21 April 2021

A new method of surgically treated nerve lesion recovery is used in Iceland

Peripheral nerve injury recovery is assessed in small mammals with nerve conduction studies 

Possible research work with an Icelandic company which promotes technologies of regenerative biological tissues, the use of fish skin and fatty acids in the cellular-therapy

Ovidiu C. Banea
21.04.2021, Reykjavik

Motor neurography of the sciatic nerve to right gastrocnemian muscle was used successfuly in a laboratory mouse (Mus musculus) and a laboratory white rat (Rattus norvegicus) on 21st of April 2021. The technique was performed by Ovidiu C. Banea (neurophysiologist) and the Aron Jónasson (biologist) at invitation of Svava Kristinsdóttir, a research scientist from Kerecis and Dr Ingvar H. Ólafsson, neurosurgeon who collaborate with the company.

The nerve microsurgery (microscope) and preparations were performed by Dr Kristín Lilja Eyglóardóttir (Neurosurgeon) and Dr Baldur Tumi Baldursson (Dermatologist). 

The "in vivo" motor neurography (nerve conduction study) in an anesthetized laboratory small mammal, might be a summation as a quantitative recovery measurement in a broader Icelandic research project. 

Motor neurography, Mus musculus 10-20 minutes after e.

CMAP from gastrocnemian muscle of euthanized Mus musculus,
Amplitude 35uV, Latency 2.5 ms.

Performing technique in euthanized Rattus norvegigus

Dr Kristín Lilja Eyglóardóttir, 
performing end-to-end neurorrhaphy of sciatic nerve "in vivo", 
Rattus norvegicus, anesthesia with Isoflurane

It seems that end-to-side suture and end-to-end suturing appear to result in equivalent axon regeneration at 12 weeks, end-to-end at 6 weeks showing better axon regeneration rate, which may reduce target organ muscle atrophy (Tateshita et al, 2018).

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